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Alpha GPC – 300 mg x 60 Capsules


Alpha GPC is a natural choline compound that is released when fatty acid found in soy and other plants break down. It is used as medicine in many parts of the world. In Europe, Alpha GPC is a prescription drug that is used to treat mental decline, specifically Alzheimer’s, dementia or stroke. On the other hand, in the United States, Alpha GPC is a dietary supplement that is sold without a prescription and promoted to improve memory.

  • Raises Brain Acetylcholine Levels
  • Improves General Cognition and Memory
  • Improves Mood and Focus
  • Improves Learning and Thinking
  • Potent Memory Booster
  • Increases Focus and Concentration

Alpha GPC helps with general cognition and has been shown to benefit with mood, memory and social behavior.

Suggested Use: As a dietary supplement, take 1 capsule at bedtime or as recommended by your health care professional.



Alpha GPC

What is Alpha GPC?

Alpha GPC is a precursor to the neurotransmitter acetylcholine which promotes healthy memory, learning, and cognition. It appears to also supports cellular membranes, and may aid in preventing cognitive decline. The main Alpha GPC benefit is the promotion of cognition, but it can supplement healthy mood and focus as well.

This supplement can benefit physical power output too, so many choose to add it to their pre-workout stack. The body is able to create small amounts of choline, but it must also be consumed from foods in order to ensure proper availability. While it can be found in some types of foods like eggs and beef liver, the amounts are usually quite small. In fact, most people today are deficient in their levels of Choline, making supplementation very important.

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Huperzine A is used as a memory booster and as a cognitive enhancer that improves neuroplasticity. It affects the cholinergic system of the brain by promoting higher levels of acetylcholine – a neurotransmitter that is essential for many of the most basic mental functions. By raising levels of acetylcholine, you can improve memory, learning, reasoning, and focus.

How Does Alpha GPC Helps:

Cognitive Health: Alpha-GPC supplements general cognition. Supplementing with Alpha-GPC promotes the translocation and activation of protein kinase C (PKC), which is responsible for short and long-term memory. Alpha-GPC also supplements learning, thinking, and memorization. Again, the translocation and activation of protein kinase C play a role in these benefits. Phosphatidylserine, when taken with Alpha-GPC, can be synergistic in aiding the supplementation of cognition.

Alzheimer’s Disease: Developing research suggests that taking 1200 mg of alpha-GPC per day significantly improves thinking skills in Alzheimer’s patients after 3 to 6 months of treatment.

Mood: Alpha-GPC supplementation can also be beneficial for mood, memory, social behavior, and more. Alpha-GPC may also influence the release of GABA, a neurotransmitter that promotes calmness.

Physical Fitness: Alpha-GPC also benefits body composition and power output during exercise.

Alpha GPC Dosage

For benefits with cognition and memory, a dosage range from 250 mg to 600 mg is recommended. Supplementation should be with with either water or a sports drink if in powder and if not, an encapsulated pill is best. For workouts, try to take about 600mg of Alpha GPC typically 45-60 minutes before the workout. This will benefit you in maximizing your performance.

This nootropic is typically well tolerated when taken at our recommended dosages and most people would take one or two doses per day. This dosage is considered safe and effective. As a beginner, we recommend you start at a lower dosage or with one capsule per day and it is very common to build up your dosage gradually after you experience the effects on a lower dosage. Alpha GPC is normally stacked well with other nootropics and in particular those of the racetam family.

Side Effects of Alpha GPC

As mentioned above, Alpha GPC is well tolerated by healthy adults and have shown to have very few side effects. However, some side effects have been reported and it is responsible to mention these reported side effects. Users of Alpha GPC have reported headaches at times, some fatigue, nervousness and nausea. In additions, others have reported dizziness and sometimes diarrhea. Always consult your healthcare professional before taking Alpha GPC.

Below are some side effects as reported; this is not a comprehensive list:

  • Heartburn
  • Headaches
  • Disorientation
  • Brain fog
  • Insomnia

While no overdose incidents have been reported and the general consensus is that it is a safe and effective supplement, users who supplement at higher dosages are more prone to experience more side effects. We highly recommend that if you are pregnant or on medication, to consult a physician before taking Alpha GPC.

How Does Alpha GPC Work?

Alpha GPC is known to increase a natural compound in the brain that occurs throughout the nervous system called acetylcholine, which functions as a neurotransmitter. Furthermore, it stimulates the production of Human Growth Hormone (HGH), which in turn can improve body composition, body fluids, muscle and bone growth. With regards to workouts, it can shorten recovery time following exercise, improve building of lean muscle mass, which makes it really beneficial for athletes.

Alpha GPC is known as a cholinergic nootropic since it increases the levels of acetylcholine neurotransmitter in the brain and compared to other choline supplements, it is higher in potency and has greater bioavailability. This means that it is known to be easily absorbed by the body and readily crosses the blood-brain barrier. This makes Alpha GPC an effective nootropic since it reaches it goal inside the nervous system rather rapidly and effectively.

One of the first actions of Alpha GPC is to increase acetylcholine levels which in turn impacts the brain in specific ways such as improving mental acuity, increasing learning skills and other cognitive processes. Another very important effect of increasing the neurotransmission in the brain is that it improves blood flow in the brain which in turn increases oxygen distribution and energy levels in the brain. The impact of that is that it can help the brain form more connections and increase speeds of thought processes which in turn improves focus, alertness and concentration.

Increasing Human Growth Hormone (HGH)

As mentioned earlier, Alpha GPC helps in the stimulation of the production of HGH levels. The HGH in the body is essential since it has a positive effect on fat burning and muscle building. Studies have shown that HGH, a peptide hormone, actually stimulates the reproduction of cells, and natural regeneration of the body by increasing the body’s metabolism.

In Europe and other countries, Alpha GPC is a prescription drug used as a medication for children with growth disorders. In fact, it is used to treat adults with growth hormone deficiency. Furthermore, it is well known in the gym and athletic communities for body building and weight lifting because it increases the levels of HGH which has the ability to increase one’s body strength and muscle mass.

HGH is also very well known with antiaging enthusiasts who consider this compound as essential in promoting longevity and general wellbeing. Alpha GPC supplementation is critical in maintaining critical body functions by increasing HGH levels in the body.

Major Benefits of Alpha GPC

Alpha GPC is the potent brain booster. It is not only an effective brain enhancer, but it also has long term benefits for brain health. Overall, Alpha GPC is effective to promote healthy cells and neurons and may also have neuroprotective properties. Most importantly, the impact of acetylcholine production provides neurotransmission at higher levels. The resulting effect is improved memory, increased learning and better analytical skills for exams and difficult mental tasks.

Following are important benefits of Alpha GPC:

  • Stimulates the production of HGH
  • Very little to no side effects
  • High Bioavailability & absorbed by body easily
  • Improves memory and cognition
  • Improves mood and social interaction
  • Treats cognitive decline associated with aging
  • Increases body composition and muscle mass
  • Used by antiaging community for longevity
  • Treats symptoms of Alzheimer’s and Dementia

In essence, the improved inter-cell communication is what really improves our focus and attention since Alpha GPC improves the out coating of each cell and makes it easier for electric pulses to flow through the cells. In fact as we age, the phospholipids in our cells are naturally declining and this leaves us exposed to natural cognitive decline and resulting in diseases of memory loss such as Alzheimer’s, dementia and stroke.

Alzheimer’s Treatment

As mentioned above, Alpha GPC is used in Europe as prescription medication for Alzheimer’s patients in higher than normal doses up to 1200 mg. Studies have shown that at this strength, patients begin to show signs of improved short and long term memory as well as increased ability to concentrate and focus on repetitive mental tasks. According to, Alpha GPC has shown in European studies to improve brain function in patients with Alzheimer’s within 3 to 6 months. Due to these results, there is a positive expectation and excitement surrounding this supplement for mental decline treatment.

Of course, the key to Alpha GPC is that it is a precursor to acetylcholine that the brains utilizes to transmit information between neurons and receptors. Overall the choline nootropics are very popular, like CDP Choline and Centrophenoxine, but Alpha GPC is the most potent.

Stroke Recovery

In a study completed by an Italian Multicenter clinical trial in 1994, it was shown that Alpha GPC had a positive therapeutic effect on patients with acute stroke or TIA. Furthermore, while some complaints were reported, such as insomnia and nausea, Alpha GPC proved to be of excellent tolerability. The study consisted of 20144 patients suffering from recent stroke or transient ischemic attacks. Alpha GPC was administered after the attack at a daily dose of 1000 mg inter-muscular for 28 days and orally at the dose of 400mg three times a day during the following 5 months after the first phase.

Alpha GPC Stacking

Alpha GPC can offer added benefits when it is used alongside other popular nootropics. The most popular stacking is with the racetam family since it displays synergy when it is stacked with a cholinergic compound. While Alpha GPC offers its unique benefits, when stacked with racetams it helps potentiate its effects. While racetams are believed to cause an increased demand for acetylcholine, Alpha GPC is believed to replenish or deliver choline in the brain which acts as a win-win situation for both Alpha GPC and the Racetams. While too much choline may result in some discomfort like headaches or nausea, the racetams help consume this to enhance their own benefits of cognitive enhancement. Therefore, both products act in tandem for multiple benefits when taken together.

Stacking with PiracetamPiracetam is a great racetam, one of the first and most popular nootropic. Piracetam has numerous studies emphasizing its benefits and effectiveness for cognitive enhancement. Taking Alpha GPC and Piracetam will definitely lead to potentiating benefits.

Stacking with Noopept – Like Piracetam, Noopept is both a cognitive enhancer but also a neuroprotection nootropic. They work well together since Noopept depletes acetylcholine while Alpha GPC stimulates production of acetylcholine and work like a buddy system to provide multiple benefits.

Alpha GPC is both safe and effective and goes well with most racetams, especially Piracetam and Noopept. All these have positive cognitive enhancement qualities and help with memory, motivation, mood and learning.

If you are pregnant or taking medication, always consult with a medical professional before taking this supplement. Otherwise, Alpha GPC is one of the safest and most effective nootropics on the market today without a prescription.

Is Alpha GPC Found in Foods?

Alpha GPC is found in eggs and red meat products and organ tissues but for the most part it is not available in its natural form. For this reason, many people have very low levels of choline. Furthermore, supplements containing Alpha GPC are made synthetically, where they can be enzymatically produced from eggs or soy lecithin. For example, just one egg yolk contains about 115mg of choline. Other sources of choline are Beef Liver, about 423 mg of choline in about 5 oz of raw liver. Also, 8 oz of fresh milk or yogurt may contain about 40 mg of choline. Lastly, vegetables such as cauliflower, cabbage and broccoli may contain about 65 mg in a cup of cooked vegetables.

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  1. Revisiting choline alphoscerate profile: a new, perspective, role in dementia? – Read Full Article
  2. Cognitive improvement in mild to moderate Alzheimer’s dementia after treatment with the acetylcholine precursor choline alfoscerate. Read Full Article
  3. The effects of acute and prolonged CRAM supplementation on reaction time and subjective measures of focus and alertness in healthy college students. Read Full Article
  4. Changes in the interaction between CNS cholinergic and dopaminergic neurons induced by L-alpha-glycerylphosphorylcholine, a cholinomimetic drug. Read Full Article
  5. Glycerophosphocholine enhances growth hormone secretion and fat oxidation in young adults. Read Full Article

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