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Aniracetam (750 mg x 30 capsules)

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Aniracetam is an analogue in the racetam family, which was developed after piracetam. It is more potent racetam that can improve memory, cognition as well as aid in creativity. Aniracetam is unique because of its unique mood enhancing effects. The nootropic reduces anxiety via interactions with serotonin, dopamine, and choline receptors. Beyond anxiety, there is evidence to suggest it can even be an alternate treatment for depression.
√ Improves Memory & Cognition
√ Improves Mood
√ Heightens Motivation
√ Reduces Anxiety & Stress
It is known to treat symptoms like restlessness, sadness, fatigue and loss of interest.

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Description


Aniracetam

What is Aniracetam?

Aniracetam belongs to the nootropic family, similar in many ways to the original piracetam (nootropil). It shares the low toxicity of piracetam, but has a larger range and stronger nootropic effects, particularly in the increasing effects of intellectual activity. In the elderly, Aniracetam has been found to improve immune function, increase resistance to infection and generate a feeling of well-being. It acts on the central nervous system (CNS), stimulating the learning process and memory. Aniracetam is currently used as a treatment for dementia and it’s being researched as a possible treatment for Alzheimer’s Disease, anxiety and depression.

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Aniracetam History

Aniracetam was developed in 1970, and is popular for its mood-enhancing effects. It is commonly used to combat social anxiety, making it ideal for public speakers or performers. In research, it has been found to promote the formation of new synapses and to enhance synaptic plasticity. What this means for you is that your brain will more easily make new connections between thoughts and memories, enabling creativity and problem solving in a newly induced calm mental environment. For Alzheimer’s and dementia patients, it also means the possibility of strengthening these connections in the brain and preventing their decay, which it has been studied extensively for.

How Does Aniracetam Works?

While the exact methods of action for Aniracetam are still not fully understood, it is clear that the supplement is able to modulate a number of different neurotransmitters. After ingestion, it quickly cross the blood-brain barrier and achieves full concentration levels within about 20 to 30 minutes. This makes it much faster acting that other racetams like piracetam.

Cholinergic Receptors
The first neurotransmitter affected by Aniracetam is Acetylcholine, a powerful brain chemical thought to be a driving force behind a number of cognitive processes including memory, learning capacity, attention span, mental energy, and more.

The supplement actually binds to the Acetylcholine receptor sites and inhibits their desensitization while also promoting greater acetylcholine release at the synapses.

This effectively results in a more active acetylcholine system which can then drive the formation of new memories and the performance of various computations.

AMPA Receptors
Many of the unique benefits of Aniracetam come from stimulation of glutamate receptors – namely the AMPA receptors and the kainate receptors. AMPA receptors are involved in fast excitatory transmission of your synapses. Aniracetam binds with these receptor sites when they are inactive and makes glutamate transmission more influential.

AMPA receptors are implicated in the induction of Long-Term Potentiation which is thought to be the process your brain uses to create new memories. By stimulating these receptors, you can effectively increase the likelihood of new information and experiences being converted into stored memories.

Serotonin and Dopamine Receptors
Aniracetam is also known to influence the neurotransmitters Dopamine and Serotonin. These are both surprisingly effective chemicals at helping to improve mood. The action involves binding to both of their receptor sites and helping to inhibit the breakdown of these chemicals.

Aniracetam is very effective at helping to restore optimal levels of both of these neurotransmitters. This means that people suffering from chemical imbalances may find fast relief, resulting in better moods and energy levels.

GABA Receptors
Aniracetam seems to increase the effects of GABAergic inhibition. GABA is important for emotional wellbeing cognition, and improving GABA function could be potentially therapeutic for anxiety and cognitive disease.

Aniracetam Benefits

Studies have shown that Aniracetam stimulates the functions of certain neuronal receptors by means of glutamic acid, bringing about memorization processes and the protection of certain nerve cells. Particularly in elderly patients cognitive function was noticeable, improving both long and short term memory in addition to learning, attention span, alertness, concentration, reasoning and absent mindedness. Consult with your medical professional before taking.

Aniracetam has been found to:

Improve Memory & Recall
Studies have shown that Aniracetam enhances both short-term and long-term memory capacity in various applications. Memory improvement, however, may range from very slight to incredibly noticeable.
Some people are able to remember detailed facts, figures, and other numbers while others may simply be able to recall specific dreams or conversations more vividly. Speed of recall is also improved for many, resulting in better test scores on online brain training exercises.

Boost Creativity and Intelligence
Aniracetam is especially effective at improving communication between the two hemispheres of the brain. This improved communication can help you to exercise both logic and creativity, leading to greater intelligence, increased creativity and better decision making and problem solving skills.

Anti-Anxiety Effects
Aniracetam has also been studied for its potential to reduce anxiety, boost mood and reduce the symptoms of depression. For people who suffer from stress and anxiety, Aniracetam may offer some relief. Many users experience a sense of peace and well-being, a reduction in anxious thoughts and even a feeling of general relaxation. Some individuals with depression report that it eases their symptoms, while others like to take it in the evening to encourage deeper and longer sleep.

Neuroprotective
Aniracetam may have neuroprotective capabilities, meaning that it may be able to help prevent damage to the brain from outside causes. In some cases, it may even be able to reverse existing damage due to such causes as heavy drinking.

Anti-depressant
Aniracetam is also known as an anxiolytic with mood-enhancing and anti-depressant qualities. If you experience stress and anxiety issues, Aniracetam may help you find some relief. It is known for promoting a feeling of well-being, ridding your mind of anxious thoughts and even producing whole-body relaxation.

Clinical Studies
Japanese and American scientists are the most active in studying the aniracetam, but there are plenty of countries that have already allowed the use of these drugs. Making sure that you are able to get rid of the social anxiety or other problems related to stress can help you to be a far more successful person and it is important to use anything that you can get your hands on. Aniracetam is one of those high quality drugs that can prove very effective for you.
There are a wide variety of aniracetam studies about the memory efficacy as well. People who have started to use racetams and other nootropics to improve their memory will find that aniracetam is one of the best short and long-term drugs. Although the aniracetam half life is very short and requires multiple doses to stay in the system, there are few side effects. The aniracetam dangers are few and far between and overall, the studies show the risk is far outweighed by the benefit.

Some people might find it hard to take any kind of synthetic drug that does not have a lot of research, which is not only safe, but totally understandable. The good thing about racetam analogues is that they all have been found a long time ago. It is important to see the impacts over the past few decades and there are a plethora of studies that can help.

Aniracetam Dosage

Aniracetam is well tolerated in high doses for long periods as long as you have no kidney or liver problems. The total daily dose could be 1500 mg in two divided doses. Some people may experience insomnia, agitation or unrest in the evening, in which case take all 1500 mg in the morning. Aniracetam is not known to interact with other drugs and can be safely taken in combination. Consult with your medical professional before taking.

Aniracetam Stacking Advice

Aniracetam + Choline Stack
The addition of a supplemental choline source usually recommended when taking racetams, such as aniracetam. Choline, an essential nutrient which we consume in our diet, is a precursor to the neurotransmitter acetylcholine which responsible for various brain functions such as memory. When it comes to pure concentrated choline content, Alpha GPC has the edge, as it contains 40 percent by weight.

Aniracetam + Sulbutiamine + Choline Stack
Aniracetam stacks well with the sulbutiamine due to its similar effects on cognition and mood, really enhancing overall effects. Meanwhile, choline works in concert with Aniracetam and sulbutiamine to ensure maximum memory power and capacity for concentrated attention. When it comes to pure concentrated choline content, Alpha GPC has the edge, as it contains 40 percent by weight.

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References:

  1. Clinical efficacy of aniracetam, either as monotherapy or combined with cholinesterase inhibitors, in patients with cognitive impairment: a comparative open study. – Read Full Article
  2. Development and validation of a liquid chromatographic method for the simultaneous determination of aniracetam and its related substances in the bulk drug and a tablet formulation. – Read Full Article
  3. Aniracetam and DNQX affect the acquisition of rapid tolerance to ethanol in mice. – Read Full Article
  4. AMPA receptors mediate passive avoidance deficits induced by sleep deprivation. – Read Full Article
  5. Pharmacokinetics and bioequivalence study of aniracetam after single-dose administration in healthy Chinese male volunteers. – Read Full Article
  6. Aniracetam: its novel therapeutic potential in cerebral dysfunctional disorders based on recent pharmacological discoveries. – Read Full Article
  7. Aniracetam enhances cortical dopamine and serotonin release via cholinergic and glutamatergic mechanisms in SHRSP – Read Full Article
  8. Effects of aniracetam after LTP induction are suggestive of interactions on the kinetics of the AMPA receptor channel. – Read Full Article
  9. Aniracetam restores the effects of amyloid-beta protein or ageing on membrane fluidity and intracellular calcium concentration in mice synaptosomes. – Read Full Article
  10. Effects of the novel compound aniracetam (Ro 13-5057) upon impaired learning and memory in rodents. – Read Full Article

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