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Colorado CBD OIL 500MG *For Pain* Buy 4, Save 20%

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Cannabidiol (CBD) Oil is one of 123 phytocannabinoid compounds in the hemp cannabis plant. The THC Content is less than 0.3%. This CBD Oil is made by “COLORADO CBD”. The FDA considers hemp oil (and it’s derivative CBD) to be a dietary supplement (not a medication), since it is made from industrial hemp plants. If you live in the US, this means you don’t need a prescription and can legally purchase and consume hemp-based cannabidiol in any state.

According to a 2013 review published in the British Journal of Clinical Pharmacology, CBD OIL may treat the following conditions:

√ Reduce Nausea and Vomiting

√ Combats Inflammatory and Pain Disorders

√ Combats Anxiety and Depression Disorders

COLORADO CBD is tested by independent laboratories to assure a consistent, dependable level of potency and quality and is 100% USA grown and extracted. It is produced with without organic solvents and NO pesticides or sprays are used on the hemp plants.

References, Research and Articles:

Cannabidiol for Neuro-degenerative Disorders

US National Library of Medicine:

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CBD OIL – Cannabidiol from hemp.  CBD offers the benefits of medical marijuana but it is 100% legal.  Through the use of selective breeding techniques, this CBD Oil has been created from cannabis varieties with high levels of CBD and negligible levels of THC.


Cannabis is the species name for the entire plant. There are several varieties of cannabis. Other well known names for Cannabis are weed and marijuana. Cannabis has long been used for hemp fibre, for hemp oils, for medicinal purposes, and as a recreational drug. The Cannabis plant contains dozens of cannabinoids, or active ingredients. The FDA considers hemp oil (and it’s derivative CBD) to be a dietary supplement (not a medication), since it is made from industrial hemp plants. If you live in the US, this means you don’t need a prescription and can legally purchase and consume hemp-based cannabidiol in any state.



However, out of all the cannabinoids, two stand out: tetrahydrocannabinol (THC) and cannabidiol (CBD). Cannabis is all about these two main Cannabinoids, THC and CBD. The main difference between THC and CBD is that THC is known for its psychoactive properties, and is the reason people feel buzzed after ingesting marijuana. On the other hand, CBD is a non-psychoactive cannabinoid and actually works to calm your high. It is also believed that CBD has numerous medicinal benefits, such as anti-inflammatory properties and the ability to protect your neurons from injury or degeneration.


Tetrahydrocannabinol (THC) is the most common psychoactive cannabinoid. It is best known for causing the high you get from smoking marijuana. However, it also seems to have a number of medical applications, such as, pain relief, nausea, depression and the ability to improve appetite, among many other things. Even after years of research, its status as an illegal drug has made information about this cannabinoid very difficult to come by. Furthermore, these are little known facts about THC, as follows: 1. THC is used in FDA-approved pharmaceuticals 2. THC can protect brain cells and stimulate their growth 3. Chemicals like THC are produced naturally in the body.

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Cannabidiol (CBD) is the second most common cannabinoid. Although it has no psychoactive effect, it appears to improve mood and alleviate pain. Interestingly, CBD has received a lot of attention lately because of its antipsychotic effect that calms the nervous system. Studies suggest that it may help with epilepsy, schizophrenia and a number of other ailments. In the latest study, published in the journal “Neuropsychopharmacology”, both Dutch and British researchers reviewed more than 66 past studies on CBD and psychosis, and concluded that the compound offers a number of advantages over current drugs. The authors point out that CBD, unlike a vast majority of medicines, appears to have no noticeable side effects and no lethal dose. Several lines of evidence, including animal and human studies, also support its effectiveness as an antipsychotic medicine.

Benefits of CBD

Scientific research now shows the many benefits of CBD Cannabidiol. CBD benefits are real because CBD does produce strong medicinal and therapeutic effects for even the most common conditions. CBD has also been shown to relieve pain and has an anti-inflammatory effect that reduces swelling. CBD may alleviate severe social anxiety and many other benefits. An increasing number of physicians, scientists and consumers are learning about these health benefits and incorporating CBD into a healthy lifestyle plan.



1. Effects of Cannabidiol (CBD) on Regional Cerebral Blood Flow. – Read Full Article

2. Cannabidiol Reduces the Anxiety Induced by Simulated Public Speaking in Treatment-Naïve Social Phobia Patients. – Read Full Article

3. The Medicinal Uses of Cannabis and Cannabinoids. – Read Full Article

4. Cannabinoids in the management of difficult to treat pain. – Read Full Article

5. Cannabinoids as novel anti-inflammatory drugs. – Read Full Article

6. Cannabinoids as therapeutic agents in cancer: current status and future implications. – Read Full Article

7. Important new clinical applications for this phytocannabinoid? – Read Full Article

8. ​Pathways and gene networks mediating the regulatory effects of cannabidiol, a nonpsychoactive cannabinoid, in autoimmune T cells – Read Full Article

​9. Analysis of endocannabinoid signaling elements and related proteins in lymphocytes of patients with Dravet syndrome. – Read Full Article

10. Antibacterial cannabinoids from Cannabis sativa: a structure‐activity study. – Read Full Article

11. CBD compound in cannabis could treat diabetes, researchers suggest. – Read Full Article

12. Regulation of nausea and vomiting by cannabinoids. – Read Full Article

13. Interaction between non‐psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti‐ nausea or anti‐emetic effects of cannabidiol (CBD) in rats and shrews. –  Read Full Article

14. Cannabidiol, a non‐psychotropic component of cannabis, attenuates vomiting and nausea‐like behaviour via indirect agonism of 5‐HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus. – Read Full Article

15. Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. – Read Full Article

16. Pure cannabidiol in the treatment of malignant migrating partial seizures in infancy: a case report. – Read Full Article

17. Cannabidiol rescues acute hepatic toxicity and seizure induced by cocaine. – Read Full Article

18. Anti‐inflammatory effects of the cannabidiol derivative dimethylheptyl‐cannabidiol ‐ studies in BV‐2 microglia and encephalitogenic T cells. – Read Full Article

19. Cannabidiol (CBD) and its analogs: a review of their effects on inflammation. – Read Full Article

20. Anti‐inflammatory and antioxidant effects of a combination of cannabidiol and moringin in LPS‐stimulated macrophages. – Read Full Article

21. The nonpsychoactive Cannabis constituent cannabidiol is a wake‐inducing agent. – Read Full Article

22. Potential Effects of Cannabidiol as a Wake‐Promoting Agent. – Read Full Article

23. Cannabidiol, a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury. – Read Full Article

24. Cannabidiol as potential anticancer drug. – Read Full Article

25. The Antitumor Activity of Plant‐Derived Non‐ Psychoactive Cannabinoids.- Read Full Article

26. Cannabis and Cannabinoids. – Read Full Article

27. Cannabinoids inhibit human keratinocyte proliferation through a non‐CB1/CB2 mechanism and have a potential therapeutic value in the treatment of psoriasis. – Read Full Article

28. The relationship between cannabidiol and psychosis: A review. – Read Full Article

29. A critical review of the antipsychotic effects of cannabidiol: 30 years of a translational investigation. – Read Full Article

30. Could cannabidiol be used as an alternative to antipsychotics? – Read Full Article

31. Cannabidiol attenuates haloperidol‐induced catalepsy and c‐Fos protein expression in the dorsolateral striatum via 5‐HT1A receptors in mice. – Read Full Article

32. Fluorinated Cannabidiol Derivatives: Enhancement of Activity in Mice Models Predictive of Anxiolytic, Antidepressant and Antipsychotic Effects. – Read Full Article

33. A systematic review of the antipsychotic properties of cannabidiol in humans. – Read Full Article

34. Multiple mechanisms involved in the large‐spectrum therapeutic potential of cannabidiol in psychiatric disorders. – Read Full Article

35. Cannabidiol Modulates Fear Memory Formation Through Interactions with Serotonergic Transmission in the Mesolimbic System. – Read Full Article

36. Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug. – Read Full Article

37. Fluorinated Cannabidiol Derivatives: Enhancement of Activity in Mice Models Predictive of Anxiolytic, Antidepressant and Antipsychotic Effects. – Read Full Article

38. Endocannabinoid system: Role in depression, reward and pain control (Review). – Read Full Article

39. Beyond the CB1 Receptor: Is Cannabidiol the Answer for Disorders of Motivation? – Read Full Article

40. Does cannabidiol have a role in the treatment of schizophrenia? Cannabinoids and schizophrenia: therapeutic prospects. – Read Full Article

41. The therapeutic potential of the phytocannabinoid cannabidiol for Alzheimer’s disease. – Read Full Article

42. Long‐term cannabidiol treatment prevents the development of social recognition memory deficits in Alzheimer’s disease transgenic mice. Fluorinated Cannabidiol Derivatives: Enhancement of Activity in Mice Models Predictive of Anxiolytic, Antidepressant and Antipsychotic Effects. – Read Full Article

43. Evidences for the anti‐panic actions of Cannabidiol. Read Full Article

44. Purified Cannabidiol, the main non‐psychotropic component of Cannabis sativa, alone, counteracts neuronal apoptosis in experimental multiple sclerosis. Read Full Article

45. The Profile of Immune Modulation by Cannabidiol (CBD) Involves Deregulation of Nuclear Factor of Activated T Cells (NFAT). – Read Full Article

46. Pathways and gene networks mediating the regulatory effects of cannabidiol, a nonpsychoactive cannabinoid, in autoimmune T cells. – Read Full Article

47. CBD & Inflammatory Bowel Disease. – Read Full Article

48. Cannabidiol, a Major Non‐Psychotropic Cannabis Constituent Enhances Fracture Healing and Stimulates Lysyl Hydroxylase Activity in Osteoblasts. – Read Full Article

49. CBD‐enriched medical cannabis for intractable pediatric epilepsy: The current Israeli experience. Read Full Article

50. Perceived efficacy of cannabidiol‐enriched cannabis extracts for treatment of pediatric epilepsy: A potential role for infantile spasms and Lennox‐Gastaut syndrome. Read Full Article

51. Cannabidiol: Promise and Pitfalls. – Read Full Article

52. HU‐446 and HU‐465, Derivatives of the Non‐psychoactive Cannabinoid Cannabidiol, Decrease the Activation of Encephalitogenic T Cells. – Read Full Article

53. A new formulation of cannabidiol in cream shows therapeutic effects in a mouse model of experimental autoimmune encephalomyelitis. – Read Full Article

54. Transdermal cannabidiol reduces inflammation and pain‐ related behaviours in a rat model of arthritis.- Read Full Article

55. Cannabidiol limits Tcell‐mediated chronic autoimmune myocarditis: implications to autoimmune disorders and organ transplantation. – . Read Full Article

56. Analysis of endocannabinoid signaling elements and related proteins in lymphocytes of patients with Dravet syndrome. – Read Full Article

57. Differential effectiveness of selected non‐psychotropic phytocannabinoids on human sebocyte functions implicates their introduction in dry/seborrheic skin and acne treatment. – Read Full Article

58. Cannabidiol increases survival and promotes rescue of cognitive function in a murine model of cerebral malaria. – Read Full Article

59. Cannabidiol improves lung function and inflammation in mice submitted to LPS‐induced acute lung injury. – Read Full Article

60. Effects of cannabidiol in the treatment of patients with Parkinson’s disease: an exploratory double‐blind trial. – Read Full Article

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